Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/24/2025

Causes of Left Shoulder Pain

Traumatic Causes

  • The American College of Radiology recommends considering fractures, including clavicle fractures, scapula fractures, and proximal humerus fractures, as the most common traumatic etiology of left shoulder pain 1, 2
  • Soft tissue injuries, such as rotator cuff tears, acromioclavicular ligament injuries, and labroligamentous complex tears, are common in traumatic left shoulder pain 1, 2, 3
  • Joint instability, including glenohumeral dislocations and acromioclavicular joint dislocations, can present as left shoulder pain 1, 2

Non-Traumatic Causes

  • The American College of Radiology suggests that degenerative conditions, such as acromioclavicular joint arthritis, are common in patients over 35-40 years with left shoulder pain 4
  • Biceps tendon pathology is a structural cause of left shoulder pain 4

Referred Pain Sources

  • Cervical spine pathology, including cervical radiculopathy and nerve compression syndromes, can manifest as left shoulder pain 4

Age-Specific Patterns

  • Patients under 35 years predominantly experience instability-related injuries, labral tears, and sports-related trauma as causes of left shoulder pain 1, 4
  • Patients over 35-40 years predominantly experience rotator cuff disease and degenerative changes as causes of left shoulder pain 4, 5

Critical Red Flag Causes

  • Septic arthritis requires immediate evaluation when systemic symptoms, such as fever, chills, or constitutional symptoms, are present 4, 5
  • Vascular compromise, including axillary artery injury, subclavian or brachial artery injury, is uncommon but debilitating 6
  • Neurological injury, including brachial plexus injury and peripheral nerve injury, can occur in the trauma setting 6

REFERENCES

1

acr appropriateness criteria® acute shoulder pain: 2024 update. [LINK]

Journal of the American College of Radiology, 2025

2

acr appropriateness criteria® acute shoulder pain: 2024 update. [LINK]

Journal of the American College of Radiology, 2025

3

acr appropriateness criteria<sup>®</sup> shoulder pain-traumatic. [LINK]

Journal of the American College of Radiology, 2018

4

Shoulder Pain Evaluation [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

5

Management of Severe Arm and Shoulder Pain in the Elderly [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

6

acr appropriateness criteria<sup>®</sup> shoulder pain-traumatic. [LINK]

Journal of the American College of Radiology, 2018