Papillary Thyroid Cancer in Hashimoto's Thyroiditis

Epidemiology and Association

• Papillary thyroid carcinoma is the most common type of thyroid cancer overall, accounting for nearly 95% of all thyroid carcinoma cases 1
• The incidence of papillary thyroid cancer in the USA is 5.7 per 100,000 person-years, with higher rates in women (8.8 per 100,000 woman-years) compared to men (2.7 per 100,000 man-years) 2

Diagnostic Considerations

• Fine-needle aspiration cytology (FNAC) remains the standard diagnostic approach for thyroid nodules in patients with Hashimoto's thyroiditis 3
• Cytologic examination of an FNA specimen from a thyroid nodule in Hashimoto's thyroiditis may be categorized as benign or suspicious for malignancy 1, 4