Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/7/2025

Femoral Endarterectomy: Risk Assessment and Considerations

  • The American College of Cardiology reports that common femoral endarterectomy (CFE) is associated with a potential for short-term morbidity, with minor or major complications occurring in 7.9% of patients 1
  • Local complications include lymphatic fistula (3.4%) 2
  • The need for procedure-related local revision is reported in 8.6% of patients 1
  • Primary patency rates of 78.5% at 7 years are observed following CFE 1

Comparison with Alternative Approaches

  • Meta-analytic data comparing CFE with endovascular interventions show similar risk of 30-day mortality and early reintervention 2
  • Endovascular approaches are associated with less procedural morbidity 1
  • Similar 1-year primary patency is observed between CFE and endovascular interventions 2
  • The need for late reintervention is similar between CFE and endovascular approaches 1

Clinical Decision Making

  • The American College of Cardiology recommends that selection of revascularization approach should be based on patient's goals 2
  • Anatomic findings should be considered when selecting a revascularization approach 1
  • Perioperative risk assessment is crucial in selecting patients for CFE 2
  • Anticipated benefit should be weighed against the risks of CFE 2
  • CFE should be reserved for patients who failed nonsurgical therapy 2
  • Favorable arterial anatomy is essential for durable results following CFE 2
  • Acceptable risk of perioperative adverse events should be considered when selecting patients for CFE 2
  • In cases where endovascular approaches may adversely affect profunda femoris artery pathways, open surgical endarterectomy is preferred 1