Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/20/2025

Naproxen Safety and Efficacy for Young Adults with Shoulder Strain

Safety Profile for Young Adults with Normal Blood Pressure

  • The American Academy of Family Physicians suggests that naproxen is generally well-tolerated for short-term use in young, healthy individuals without pre-existing cardiovascular, renal, or gastrointestinal conditions 1
  • The 3-day duration minimizes risk of adverse effects, as most NSAID complications occur with prolonged use or in high-risk populations 1, 2

Risk Assessment for This Specific Patient

  • Young age (23 years) is protective against most NSAID-related complications, as risk increases linearly at approximately 4% per year of advancing age 2
  • Short duration therapy (3 days) significantly reduces risk compared to chronic use 1, 3

Precautions to Consider

  • Patient should be advised to take naproxen with food to minimize potential gastrointestinal irritation 1
  • If pain persists beyond 3 days, reevaluation is recommended rather than continuing naproxen long-term 1
  • Patient should be advised to avoid alcohol while taking naproxen to reduce risk of gastrointestinal irritation 1