Baseline and Ongoing Laboratory Monitoring for Lithium Therapy

Baseline Assessment

• Prior to initiating lithium carbonate, clinicians should obtain a complete blood count, thyroid function tests, blood urea nitrogen and creatinine levels, and a pregnancy test in individuals of child‑bearing potential. These baseline investigations are recommended by the American Academy of Child and Adolescent Psychiatry to ensure safe initiation of therapy【1】【2】.

Routine Follow‑up Monitoring

• Once a stable lithium dose has been achieved, serum lithium concentrations, renal function (BUN/creatinine), thyroid function, and a urinalysis should be re‑checked every 3–6 months to maintain therapeutic efficacy while minimizing toxicity. This schedule is endorsed by the American Academy of Child and Adolescent Psychiatry【1】【2】.