Furosemide-Induced Vestibulotoxicity

Mechanism and Risk Factors

• Furosemide can cause ototoxicity affecting both the vestibular and auditory systems, resulting in balance disturbances and hearing impairment, as reported by the American Thoracic Society and the Centers for Disease Control and Prevention 1, 2
• The risk of vestibulotoxicity is significantly increased in advanced age, according to the Centers for Disease Control and Prevention 2

Special Considerations

• In patients with tuberculosis receiving streptomycin, the concomitant use of furosemide significantly increases the risk of vestibular damage, as noted by the American Thoracic Society and the Centers for Disease Control and Prevention 1, 2
• The elderly are more susceptible to furosemide-induced vestibulotoxicity and require careful monitoring, as recommended by the Centers for Disease Control and Prevention 2