Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/24/2025

Ureterovaginal Fistula Causes and Management

Main Causes

  • The primary cause of ureterovaginal fistula is iatrogenic injury during pelvic surgery, particularly gynecological procedures such as hysterectomy, where an initially unrecognized ureteral injury can present in a delayed manner as a ureterovaginal fistula 1, 2
  • Obstetric/vaginal trauma accounts for a significant portion of cases, with similar mechanisms leading to ureterovaginal fistulas 3
  • Penetrating pelvic trauma can directly damage the ureter and lead to fistula formation 1
  • Radiation therapy for gynecological malignancies can cause tissue damage leading to fistula formation 3, 4
  • Pelvic malignancies can invade the ureter and vagina, creating a pathological connection 3

Diagnostic Considerations

  • CT with intravenous contrast and delayed imaging is currently the most common method for evaluating urinary extravasation 5
  • Water-soluble contrast may be used to opacify fistulous tracts 3

Management

  • According to the American Urological Association (AUA) guidelines, patients with ureterovaginal fistula should be initially managed with ureteral stent placement when possible 1
  • Ureteral stenting has become the first-line treatment in uncomplicated ureterovaginal fistulas, with success rates of 64-100% 1
  • Transureteroureterostomy may be recommended in cases of stent failure 1
  • Surgical approaches may be open, laparoscopic, or robot-assisted, with success rates approaching 100% for reimplantation procedures 1

Important Clinical Considerations

  • Early recognition of ureteral injury during pelvic surgery is crucial to prevent fistula formation 2
  • Preventive measures during pelvic surgery, including careful identification of ureters, can significantly reduce the risk of this complication 2