Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/23/2025

Enterobiasis Diagnosis and Treatment

Clinical Context

  • Pinworm infection, also known as enterobiasis or threadworm infection, is caused by Enterobius vermicularis and represents one of the most common helminthic infections worldwide, particularly affecting children aged 5-14 years 1, 2, 3, 4

Key Clinical Features for Documentation

  • Pruritus ani (intense nocturnal perianal itching) is the most common presenting symptom, supporting the diagnosis of enterobiasis 1, 2, 3, 4, 5
  • Gastrointestinal symptoms, including diarrhea, abdominal pain, and weight loss, are associated with enterobiasis 1, 2, 3, 4
  • Vaginal discharge in females due to genital tract colonization is a clinical feature of enterobiasis 1, 2, 3, 4
  • Behavioral changes, such as irritability and sleep disturbance, are associated with enterobiasis 5

Diagnostic Confirmation

  • The cellophane tape test (sellotape test) is the gold standard diagnostic method for enterobiasis, performed by placing adhesive tape on perianal skin and examining microscopically for ova 5, 6

Treatment Documentation

  • Albendazole 400 mg as a single oral dose, repeated in 2 weeks, is a standard treatment regimen for enterobiasis 5, 6
  • Mebendazole 100 mg as a single oral dose, repeated in 2 weeks, is a standard treatment regimen for enterobiasis 5, 6

Important Coding Considerations

  • The infection is worldwide in distribution, particularly affecting children 1, 2, 3, 4
  • Transmission of enterobiasis occurs via the fecal-oral route 5
  • The prepatent period of enterobiasis is 2-4 weeks 5