Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 6/30/2025

Aripiprazole Dosage and Administration in Bipolar Disorder

Patient-Specific Dose Adjustments

  • For poor metabolizers of CYP2D6, the dose of aripiprazole should be reduced, according to the American College of Clinical Pharmacology 1

Metabolic Monitoring

  • Regular monitoring of metabolic parameters is essential in bipolar patients, as they have higher rates of metabolic syndrome, as recommended by the American Psychiatric Association 2

REFERENCES

2

Bipolar Disorder Treatment Guidelines [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025