Motion Sickness Prevention and Treatment

Pharmacological Management

• Prolonged use of vestibular suppressants like scopolamine can interfere with central compensation in peripheral vestibular conditions, according to the American College of Medical Toxicology 1
• Scopolamine can cause significant adverse effects including blurred vision, dry mouth, dilated pupils, urinary retention, and sedation, as reported by the American Academy of Clinical Toxicology 1
• Anticholinergic medications are a significant independent risk factor for falls, especially in elderly patients, as stated by the American Geriatrics Society 1

Prevention of Anticipatory Symptoms

• The best approach to prevent anticipatory nausea and vomiting is optimal control of acute symptoms, as recommended by the European Society for Medical Oncology 2
• Behavioral therapies such as progressive muscle relaxation training, systematic desensitization, and hypnosis can effectively treat anticipatory symptoms, according to the American Society of Clinical Oncology 2
• Benzodiazepines can reduce anticipatory symptoms, but their efficacy tends to decrease with continued use, as noted by the National Comprehensive Cancer Network 2