Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/25/2025

Triple Therapy for COPD Management

Clinical Guidelines and Recommendations

  • The Canadian Thoracic Society recommends single inhaler triple therapy (SITT) for patients with persistent moderate to severe dyspnea and/or poor health status despite treatment with dual therapy, as it may reduce mortality in individuals with moderate-severe disease 1
  • The Canadian Thoracic Society suggests SITT for patients at high risk of COPD exacerbations due to its potential to reduce mortality in individuals with moderate-severe disease 1