Amlodipine Dosing Recommendations
Clinical Practice Guidelines
- The American College of Cardiology recommends amlodipine as a once-daily medication at doses of 2.5-10 mg for adults 1
- Amlodipine is administered once daily in pediatric patients, with doses up to 5 mg showing efficacy 2
- Calcium channel blockers like amlodipine are considered effective options for hypertension management, with standard adult dosing being 5-10 mg once daily 1
Pharmacokinetic Considerations
- Amlodipine's long half-life (approximately 30-50 hours) supports once-daily dosing, unlike some other calcium channel blockers that require multiple daily dosing 1
Amlodipine Dosing Guidelines
Special Considerations
- The American Heart Association considers amlodipine safe for breastfeeding with a relative infant dose of 1.7%-4.3% 3
Potential Adverse Effects
- The American College of Cardiology notes that other potential side effects of amlodipine include headache, flushing, and dizziness 4