Meropenem Dosing for Elderly Patients with Urosepsis and Renal Impairment

Assessment of Renal Function

• Elderly patients often have decreased renal function even with normal serum creatinine levels due to age-related decline in muscle mass 1

Special Considerations for Elderly Patients

• The American Society of Nephrology recommends monitoring renal function during therapy, especially in elderly patients whose renal function may change during the course of treatment 2

Monitoring Recommendations

• The National Kidney Foundation suggests assessing clinical response within 48-72 hours to determine efficacy and reassessing renal function every 2-3 days to adjust dosing as needed 2