Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 1/7/2026

Optimal Pituitary MRI Protocol

Core Imaging Sequence Requirements

Contrast Administration

Field‑Strength Selection

Technical Specification Parameters

Parameter Recommended Value Reference
Field of view ≤ 256 mm, focused on sellar region 6
Frequency / phase encoding ≥ 172 each 6
Number of excitations (NEX) ≥ 1 6
Slice gap / spacing 0 mm (contiguous slices) 6
Scan time per sequence ≈ 5–10 min 6
T1‑pre‑contrast (3D) TR ≈ 2100 ms, TE minimum, TI ≈ 1100 ms, flip angle 10–15°, sagittal or axial 6
T2‑weighted Fast or turbo spin‑echo, coronal plane 1
T1‑post‑contrast Identical parameters to pre‑contrast for direct comparison 6
Volumetric gradient‑echo post‑contrast 3D acquisition for isotropic resolution 3

Interpretation and Pitfalls

Advanced Imaging for Equivocal Cases