Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/3/2025

Neurostorming in Brain Injury

Characteristics of Neurostorming

  • Neurostorming, also known as paroxysmal sympathetic hyperactivity (PSH), is characterized by episodes of tachycardia, hypertension, tachypnea, hyperthermia, diaphoresis, and posturing, according to Praxis Medical Insights 1
  • Symptoms of neurostorming typically occur in a paroxysmal pattern with periods of relative normalcy between episodes, as noted by Praxis Medical Insights 2
  • Episodes of neurostorming can be triggered by external stimuli such as repositioning, suctioning, or other care activities, as reported by Praxis Medical Insights 1

Brain Injury Patterns Associated with Neurostorming

  • Hypoxic-ischemic brain injury can trigger neurostorming without diffuse axonal injury being present, as found in a study published in Circulation 3
  • Symptomatic hypoxic-ischemic injury with diffuse brain cell death can present with global neurological signs, according to the Journal of the American College of Cardiology 4
  • Focal traumatic lesions affecting autonomic centers or pathways can cause neurostorming, as noted by Praxis Medical Insights 2

Diagnostic Considerations

  • Non-contrast CT is the first-line imaging modality in acute traumatic brain injury but has limitations in detecting both diffuse axonal injury and early signs of neurostorming, as stated by Praxis Medical Insights 1
  • MRI is indicated when CT results are normal but persistent unexplained neurologic findings are present, according to Praxis Medical Insights 1, 2

Management Implications

  • Management of neurostorming focuses on symptom control regardless of underlying etiology, as recommended by Praxis Medical Insights 2
  • Treatment strategies for neurostorming include maintaining adequate cerebral perfusion with systolic BP >110 mmHg, as suggested by Praxis Medical Insights 2
  • Controlling ventilation through intubation and mechanical ventilation when necessary is a treatment strategy for neurostorming, as noted by Praxis Medical Insights 2
  • Preventing secondary brain injury through avoidance of hypocapnia is a key aspect of neurostorming management, according to Praxis Medical Insights 2
  • Early physical therapy to prevent contractures is a recommended treatment strategy for neurostorming, as stated by Praxis Medical Insights 2