Management of IgE-Mediated Food Allergies

Introduction to Xolair Therapy

• The American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma and Immunology Joint Task Force notes that Xolair therapy may reduce the risk of anaphylaxis from accidental food exposure and improve quality of life by reducing anxiety related to accidental exposures 1

Guidelines for Xolair Administration

• The American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma and Immunology Joint Task Force recommends in-office administration of Xolair due to the black box warning for anaphylaxis, patient/family anxiety about self-administration, and the need for 2-hour observation for the first 3 doses 1

Management of IgE-Mediated Food Allergies without Xolair

• Current guidelines recommend strict dietary avoidance of allergens 2
• Epinephrine auto-injector availability is recommended for patients with IgE-mediated food allergies 3
• Education on food label reading and cross-contamination is also recommended 2

Ongoing Management with Xolair

• While on Xolair therapy, patients must continue strict food allergen avoidance measures, maintain epinephrine availability for emergency use, undergo regular monitoring for treatment response, and document any accidental exposures and reactions 1