Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/7/2025

Treatment Options for Undescended Testis (Cryptorchidism)

Evaluation and Timing of Treatment

  • Infants with cryptorchidism detected at birth who do not have spontaneous testicular descent by 6 months should be referred to an appropriate surgical specialist 4
  • Boys with newly diagnosed cryptorchidism after 6 months of age should also be promptly referred to a surgical specialist 4
  • Imaging studies are not recommended prior to referral as they rarely assist in decision making 4
  • For phenotypic male newborns with bilateral nonpalpable testes, immediate specialist consultation is required to evaluate for possible disorders of sex development 4

Rationale for Treatment

  • Early surgical intervention reduces the risk of impaired fertility potential 4
  • Testes that remain undescended by 6 months are unlikely to descend spontaneously 4
  • Continued damage may occur to testes that remain in a non-scrotal location 4
  • Treatment addresses increased risks of impaired fertility potential 4, testicular malignancy 1, testicular torsion 1, and associated inguinal hernia 1, 2, 3

Important Considerations

  • Successful scrotal repositioning of the testis may reduce but does not completely prevent the potential long-term risks of infertility and testicular cancer 1, 2, 3
  • Hormonal therapy alone is not recommended as primary treatment for cryptorchidism 4
  • For bilateral nonpalpable testes in a phenotypic male newborn, immediate specialist consultation is required to rule out disorders of sex development 4
  • A newborn with bilateral nonpalpable gonads should not be circumcised until after workup is complete 4
  • When cryptorchidism is present with phallic anomalies, evaluation for disorders of sex development should be considered 4

Follow-up

  • Appropriate counseling and follow-up is essential after treatment 1, 2, 3
  • Monitoring for testicular position and development should continue throughout childhood and adolescence 1, 2, 3

REFERENCES

1

Referral for Babies with Cryptorchidism [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025