Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/29/2025

Diagnostic Approach and Treatment of Adenomyomatosis of the Gallbladder

Imaging and Diagnostic Techniques

  • Contrast-enhanced ultrasound (CEUS) can help differentiate adenomyomatosis from other gallbladder lesions, as reported in Radiology 1
  • CT scan may show "rosary sign" but has lower diagnostic accuracy than MRI, as noted in Radiology 1

Treatment Algorithm

  • Laparoscopic approach is preferred when feasible for symptomatic adenomyomatosis, as recommended by the American College of Physicians, with evidence from Annals of Internal Medicine 2, 3
  • Surgery should be performed by experienced surgeons to minimize complications, as advised by the American College of Surgeons, with evidence from Annals of Internal Medicine 2, 3
  • Open or laparoscopic cholecystectomy are both appropriate options, with laparoscopic cholecystectomy offering reduced recovery time but requiring appropriate surgical expertise, as reported in Annals of Internal Medicine 2, 3, 4

Surgical Considerations

  • The potential risk of bile duct injury should be considered, especially with laparoscopic approach, as noted in Annals of Internal Medicine 3, 4