Renal Dose Adjustment for Ciprofloxacin

Indications for Dose Adjustment

• Ciprofloxacin dosing should be adjusted when a patient’s creatinine clearance falls below 30–50 mL/min, indicating significantly impaired renal function. 1
• The American Geriatrics Society’s consensus guidelines, developed by geriatric clinical pharmacists, advise that older adults with renal impairment receive either a 50 % dose reduction or an extension of the dosing interval for ciprofloxacin. 1