Sotatercept in Pulmonary Arterial Hypertension

Clinical Guidelines and Management

• The American Thoracic Society, as published in Chest, recommends a multidisciplinary approach to treatment with combination therapy for patients who remain symptomatic on initial therapy 1
• The European Respiratory Society, as published in the European Respiratory Review, suggests that patients with PAH should be managed at specialized pulmonary hypertension centers with a multidisciplinary approach 2
• General measures for PAH patients remain important, including avoiding excessive physical activity, pregnancy, high altitude exposure without supplemental oxygen, and non-essential surgery, as recommended by the American Thoracic Society and the European Respiratory Society 1, 2
• Vaccination against influenza and pneumococcal pneumonia is recommended for PAH patients, as suggested by the American Thoracic Society 3
• When surgery is necessary for PAH patients, care should be coordinated at a pulmonary hypertension center with careful monitoring of clinical status, oxygenation, and hemodynamics, as recommended by the American Thoracic Society 1, 3