Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/14/2025

Management of Pregnancy at 40 Weeks Gestation

Evidence for Induction at 40 Weeks

  • The American College of Obstetricians and Gynecologists recommends elective induction of labor at 39 weeks 0-4 days as a reasonable option for low-risk nulliparous women with reliable dating 1
  • Elective induction of labor at 39 weeks is associated with reduced cesarean delivery rates (18.6% vs 22.2%) compared to expectant management 1
  • Reduced incidence of hypertensive disorders of pregnancy (9.1% vs 14.1%) with elective induction compared to expectant management 1

Special Considerations

  • For pregnancies with fetal growth restriction (FGR) and normal Doppler studies, delivery is recommended at 38-39 weeks gestation 2
  • For FGR with decreased diastolic flow, delivery is recommended at 37 weeks gestation 2
  • For women with cardiac disease, induction of labor at 40 weeks is recommended to avoid complications associated with prolonged pregnancy 3
  • In women at high risk for valve thrombosis requiring anticoagulation, planned delivery may be necessary to minimize the period off anticoagulation 4

Mode of Delivery Considerations

  • Vaginal delivery is recommended for most women, with cesarean section reserved for obstetric indications 4
  • Epidural anesthesia is recommended to avoid the stress of pain during delivery 3
  • For high-risk patients with cardiac disease, elective cesarean section should be considered to maintain more stable hemodynamics 3

Practical Approach to Management

  • Confirm accurate dating of pregnancy before making decisions about induction 1
  • Discuss the benefits and risks of induction versus expectant management with the patient 1
  • If induction is chosen, use appropriate cervical ripening methods for unfavorable cervix 1
  • Allow adequate time for labor progress during the induction process 1
  • Monitor fetal well-being throughout labor with appropriate fetal surveillance 5

REFERENCES

1

Management of Pregnancy Beyond 39 Weeks [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

2

Timing of Delivery for Fetal Growth Restriction (FGR) with Abnormal Dopplers [LINK]

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

5

acr appropriateness criteria assessment of fetal well-being. [LINK]

Journal of the American College of Radiology, 2016