Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/25/2025

Treatment of Eczema Behind the Ears

First-Line Treatment Approach

  • The British Medical Journal recommends starting with mild to moderate potency topical corticosteroids for retroauricular eczema, as this is a thinner-skinned area where potent steroids carry higher risk of adverse effects 1
  • Apply a mild to moderate potency topical corticosteroid, such as hydrocortisone 1-2.5% or prednicarbate 0.02% cream, to the affected area 1-2 times daily, combined with regular use of emollients and soap-free cleansers, as suggested by the British Medical Journal 1

Essential Adjunctive Measures

  • Liberal use of emollients is the cornerstone of maintenance therapy and should be applied regularly, even when the eczema appears controlled, according to the British Medical Journal 1
  • Use soap-free cleansers and avoid alcohol-containing products on the affected area, as recommended by the Annals of Oncology 2, 3

Managing Pruritus (Itching)

  • Sedating antihistamines, such as diphenhydramine or clemastine, may help with nighttime itching through their sedative properties, not through direct anti-pruritic effects, as stated by the British Medical Journal and the Annals of Oncology 1, 2

Infection Surveillance

  • Watch for signs of secondary bacterial infection, such as increased crusting, weeping, or pustules, and if suspected, add flucloxacillin as first-line antibiotic for Staphylococcus aureus, as recommended by the British Medical Journal 1
  • If you observe grouped vesicles, punched-out erosions, or sudden deterioration with fever, suspect eczema herpeticum and initiate intravenous acyclovir immediately, which is a medical emergency requiring early treatment, according to Praxis Medical Insights 4

Safety Considerations for Elderly Patients

  • The retroauricular area is at higher risk for atrophy, so avoid very potent corticosteroids in this location, and limit continuous use and implement "steroid holidays" when possible, as suggested by the British Medical Journal 1

When to Refer

  • Refer the patient if there is failure to respond to moderate potency topical corticosteroids after 4 weeks, or if systemic therapy or phototherapy is needed, as recommended by the British Medical Journal 1