Anti-DFS70 Antibody Clinical Significance

Diagnostic Considerations

• The presence of rheumatoid factor, as detected by testing, is an important consideration in the diagnosis of autoimmune diseases, according to the American College of Allergy, Asthma, and Immunology 1, 2
• Never initiate immunosuppressive therapy based solely on a positive ANA or anti-DFS70 without disease-specific autoantibodies and compatible clinical manifestations, as recommended by the European League Against Rheumatism 3, 1, 2

Management and Treatment

• The American College of Rheumatology recommends managing patients with anti-DFS70 and coexisting disease-specific autoantibodies according to the specific autoimmune disease identified by the disease-marker autoantibodies 1, 2