Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 10/9/2025

Losartan and Palpitations

Adverse Event Profile

  • Losartan has a notably favorable cardiac tolerability profile compared to many other antihypertensive agents, particularly regarding symptomatic bradycardia or rhythm disturbances, as reported by the American Heart Association 1

Clinical Monitoring

  • Monitor serum electrolytes and renal function within 1-2 weeks of initiating losartan, as metabolic disturbances could manifest as palpitations, according to the European Society of Cardiology 2