Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/4/2025

Treatment Guidelines for Aripiprazol vs. Cariprazina

Patient Profile

  • The American Academy of Child and Adolescent Psychiatry recommends aripiprazol for children and adolescents with schizophrenia, tic disorders, OCD, or autism spectrum disorder 2
  • The Lancet Psychiatry suggests that patients with first-episode psychosis or early-stage schizophrenia may benefit from aripiprazol 1
  • Patients with difficulty swallowing may benefit from aripiprazol, which is available in multiple formulations 3

Treatment Considerations

  • For patients with refractory schizophrenia who have failed two antipsychotics (including one atypical), clozapina should be considered before aripiprazol or cariprazina, according to The Lancet Psychiatry and the Journal of the American Academy of Child and Adolescent Psychiatry 1, 4