Dosing and Safety Guidelines for Paracetamol and Metoclopramide in Children

Paracetamol (Acetaminophen) Dosing

For pediatric patients, the recommended dose is 10–15 mg per kilogram of body weight every 4–6 hours, not to exceed 75 mg/kg per day or 4 g per day (whichever is lower). This recommendation applies to an 8‑year‑old child and is based on weight‑based calculations. 1

The standard pediatric dose is 0.1 mg per kilogram of body weight per administration, with a maximum of 10 mg per dose. 1
Doses may be repeated every 6–8 hours as needed, respecting the maximum single‑dose limit. 1

Metoclopramide must never be combined with tramadol in any pediatric patient. This is an absolute contraindication. 1
Metoclopramide is contraindicated in children younger than 1 year. 1

Weight‑based calculation: Always weigh the child and compute doses based on actual kilograms before administration. 1
Check for contraindicated co‑medications: Prior to giving metoclopramide, verify that tramadol is not being used concurrently. 1
Avoid prohibited combinations: Do not administer metoclopramide together with tramadol under any circumstances. 1
Age restriction compliance: Do not give metoclopramide to infants under 1 year of age. 1