Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/23/2025

Ocrelizumab Treatment for Primary Progressive Multiple Sclerosis

Patient Clinical Status and Treatment Response

  • The patient exhibits typical PPMS manifestations including progressive triparesis, fatigue, muscle spasms, neuropathic pain, balance/gait problems, and neurogenic bladder requiring a suprapubic catheter, as described in Nature Reviews Neurology 1

Monitoring Recommendations

  • Continue regular neurological assessments to monitor disease progression, as recommended by Nature Reviews Neurology 2