Modafinil Dosing in End-Stage Renal Disease (ESRD)

Dosing Recommendations

• For patients on hemodialysis, the American Society of Nephrology recommends administering modafinil after dialysis sessions on dialysis days 1
• The general approach to modafinil dosing in ESRD follows principles for medication dosing in renal impairment, as suggested by Clinical Infectious Diseases guidelines 1