Lip Fillers and Autoimmune Issues

Alternative Options with Lower Immunogenic Potential

• Autologous Platelet Concentrates (APCs) may offer a promising alternative for lip rejuvenation with potentially lower immunogenic risk, providing rejuvenation effects rather than significant volumizing, with benefits including color improvement, biostimulation, and improvement of dermal structure and moisture 1
• APCs are administered via needle (27-30 gauge) or cannula (25 gauge), with 0.2-0.5 mL injected per quadrant, and can be considered for patients with autoimmune conditions who still desire lip enhancement 1
• The American Academy of Periodontology recommends using APCs instead of HA fillers for a more natural rejuvenation effect, with moderate strength of evidence 1, 2