Dosage and Frequency of MDI Levosalbutamol in Adults

Standard Dosing Guidelines

• The standard MDI levosalbutamol (45 mcg/puff) dosing follows the same pattern as albuterol MDI dosing according to national asthma guidelines 1, 3
• For acute asthma exacerbations, 4-8 puffs should be administered every 20 minutes for 3 doses, then every 1-4 hours as needed 2, 3
• Levosalbutamol is administered in half the milligram dose of albuterol for comparable efficacy and safety 1

Administration Technique

• For optimal delivery, MDI should be used with a valved holding chamber (VHC) 2, 3
• In mild-to-moderate exacerbations, MDI with proper administration technique and coaching by trained personnel is as effective as nebulized therapy 2

Special Considerations

• For severe exacerbations, consider adding ipratropium bromide MDI (8 puffs every 20 minutes for up to 3 hours) to levosalbutamol therapy 2, 3