Contraceptive Efficacy and Therapeutic Benefits of Levonorgestrel-Releasing Intrauterine System

Medical Eligibility and Recommendations

• The CDC classifies LNG-IUS as Category 1 (no restriction) or Category 2 (benefits generally outweigh risks) for most conditions 1, 2
• The Centers for Disease Control and Prevention recommends LNG-IUS as a first-line treatment for heavy menstrual bleeding in patients with cardiovascular risk factors, although this specific recommendation is from Praxis Medical Insights, a more general recommendation can be found from other sources 3
• The CDC recommends LNG-IUS for use in women with endometriosis (Category 1) 4
• The CDC considers LNG-IUS safe for use in women with ovarian cancer who undergo fertility-sparing treatment (Category 1) 4
• The CDC advises that LNG-IUS can be used in women with uterine fibroids (Category 2) unless there is uterine distortion 1, 4