Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/17/2025

Referral Criteria for Patients with Kidney Stones

Emergency Department Referral Criteria

  • Patients with acute renal colic who cannot be assessed within 30 minutes should be sent to the emergency department 1, 2
  • Failure of pain control with analgesia within one hour requires immediate hospital admission 3
  • Patients with shock or fever must be admitted to hospital immediately due to risk of sepsis 1
  • Abrupt recurrence of severe pain after initial relief warrants immediate admission 3
  • Patients with a single kidney and acute obstruction should be referred to the emergency department 4
  • Abnormal vital signs, particularly tachycardia, hypotension, or fever, require emergency department referral 1
  • Patients over 60 years with flank pain should be referred to the emergency department to rule out abdominal aortic aneurysm 2
  • Women with delayed menses and flank pain should be referred to the emergency department to rule out ectopic pregnancy 2

Urologist Referral Criteria

  • Recurrent or extensive nephrolithiasis should be referred to a urologist 5, 6
  • Patients with solitary kidney and kidney stones should be referred to a urologist 4
  • Patients with bilateral obstructing stones should be referred to a urologist 4
  • The European Urology Association recommends medical expulsive therapy (alpha-blockers) for stones ≤10mm in the distal ureter 4

Management Algorithm Before Referral

  • Diagnose based on history of abrupt onset of severe unilateral flank pain radiating to groin/genitals 1, 2
  • Perform urinalysis - presence of hematuria supports diagnosis (>80% of renal colic cases) 1
  • Administer analgesia promptly - diclofenac 75mg intramuscular injection is preferred 2
  • Follow up by phone within one hour to assess pain control 3
  • If pain is not controlled within one hour, arrange immediate hospital admission 3
  • All patients with suspected renal colic should receive follow-up imaging to confirm diagnosis 3
  • Patients managed at home should increase fluid intake and strain urine to catch any passed stones 3

Special Considerations

  • Patients with known chronic kidney disease and nephrolithiasis should be referred to nephrology, as recommended by the American Journal of Kidney Diseases 5, 6
  • Patients with uric acid stones may benefit from oral chemolysis with urinary alkalinization, according to the European Urology association 4
  • Patients on antithrombotic therapy require special consideration before interventional procedures, as stated by the European Urology association 4