Treatment of Major Depressive Disorder with Desvenlafaxine

Recommended Therapeutic Approach

• The American College of Physicians recommends either cognitive behavioral therapy or second-generation antidepressants (including desvenlafaxine) for treating major depressive disorder after discussing treatment effects, adverse effects, cost, accessibility, and patient preferences 1, 2
• Desvenlafaxine is classified as a second-generation antidepressant (serotonin-norepinephrine reuptake inhibitor) with demonstrated efficacy in multiple fixed-dose trials at 50 mg daily 3