Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/3/2025

Treatment of Pilonidal Cysts

Surgical Management

  • Incision and drainage is the primary treatment for inflamed pilonidal cysts, allowing for thorough evacuation of pus and probing of the cavity to break up loculations 1, 2
  • For recurrent abscesses at a site of previous infection, search for local causes such as a pilonidal cyst, which should be drained and cultured early in the course of infection 1, 3
  • After surgical drainage, the wound can be managed in one of two ways: open wound healing (secondary intention) by simply covering the surgical site with a dry dressing 2, or closed wound healing (primary closure) by suturing the wound closed 2

Antibiotic Therapy

  • Systemic antibiotics are generally unnecessary for uncomplicated pilonidal cysts after incision and drainage unless there is extensive surrounding cellulitis or systemic signs of infection 1, 2
  • For recurrent pilonidal abscesses, a 5-10 day course of antibiotics active against the cultured pathogen may be considered 1