Switching from Ropinirole to Pramipexole

Clinical Monitoring and Dose Adjustment

• The American Geriatrics Society recommends monitoring for typical dopaminergic adverse effects including orthostatic hypotension, somnolence, nausea, and hallucinations, particularly in elderly patients 1, 2
• The American Geriatrics Society suggests being prepared to adjust the pramipexole dose based on efficacy and tolerability, as individual responses may vary, and in elderly patients, start with the lowest effective dose (0.125 mg) and monitor blood pressure, renal function, and fall risk closely 2