Treatment of Major Depressive Disorder with Vortioxetina

Duration of Treatment

• The American College of Physicians recommends continuing treatment for 4-9 months after a satisfactory response in patients with a first episode of major depressive disorder, according to the Annals of Internal Medicine 1
• Patients with 2 or more episodes may benefit from therapy for years to a lifetime, as suggested by the Annals of Internal Medicine 1

Monitoring

• The American Medical Association recommends evaluating the patient's status, therapeutic response, and adverse effects within 1-2 weeks of starting therapy, as stated in the Annals of Internal Medicine 1
• Monitoring should especially focus on suicidal thoughts and behaviors, mainly during the first 1-2 months when the risk is higher, according to Praxis Medical Insights 2

Treatment Response

• The treatment response should be assessed after 6-8 weeks, and if there is no adequate response, the treatment should be modified, as recommended by the Annals of Internal Medicine and Praxis Medical Insights 1, 2