Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/23/2025

Pregabalin Use in Dialysis Patients

Patient Considerations

  • Patients with kidney disease often have a higher symptom burden, including cognitive symptoms, which may be exacerbated by medications, according to the Kidney International guidelines 1
  • Dialysis patients typically take 5-14 medications daily, increasing the risk of drug interactions and adverse effects, as noted by the American Journal of Kidney Diseases 2
  • Regular assessment of neurological symptoms is recommended for dialysis patients on pregabalin, with symptom burden regularly assessed using standardized tools to detect medication-related adverse effects, as suggested by Kidney International 1

Medication Management

  • Medication reconciliation is particularly important for dialysis patients to identify potential medication-related problems, as emphasized by the American Journal of Kidney Diseases 2