Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/14/2025

Side Effects of Dutasteride for Hair Growth

Common and Hormonal Side Effects

  • Patients using dutasteride for hair growth should be aware of sexual side effects including erectile dysfunction, decreased libido, and ejaculation disorders, which occur in approximately 2-4% more patients compared to placebo 1
  • Breast-related side effects, such as gynecomastia and breast tenderness, occur in approximately 2.3% of patients compared to 0.74% on placebo 2
  • Reduction in PSA levels by approximately 50% after 12 months of therapy, which must be considered when interpreting PSA results for prostate cancer screening 1

Important Precautions and Monitoring

  • The American Urological Association recommends considering the effect of dutasteride on PSA values when interpreting PSA results for prostate cancer screening, as dutasteride lowers PSA values by approximately 50% after 12 months 1