Discontinue Trazodone and Do Not Use Clonidine for Chronic Insomnia

Guideline Recommendations Against Trazodone

Lack of Evidence for Clonidine

Risks Associated with Antipsychotics for Insomnia

Evidence‑Based First‑Line Pharmacologic Options

Non‑benzodiazepine BZRAs (zolpidem, eszopiclone, zaleplon)

Low‑dose Doxepin (3–6 mg)

Non‑Pharmacologic First‑Line Therapy

Medications to Avoid

First‑Line Management of Chronic Insomnia: Cognitive Behavioral Therapy for Insomnia (CBT‑I)

Recommendation

Core Components of CBT‑I