Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/8/2025

Cystitis Glandularis Management

Diagnostic and Treatment Approach

  • Antibiotics should be administered if there is evidence of concurrent bacterial infection, as recommended by the European Association of Urology 1
  • Regular cystoscopic surveillance is recommended at 3-6 month intervals for the first 2 years, according to the National Comprehensive Cancer Network 2
  • Urinary cytology should be performed periodically to monitor for potential malignant transformation, as suggested by the National Comprehensive Cancer Network 2
  • Upper tract imaging should be considered every 1-2 years for high-risk cases, as recommended by the National Comprehensive Cancer Network 2
  • For cystitis symptoms, first-line options include nitrofurantoin (100 mg twice daily for 5 days) if renal function is adequate, as recommended by the American Urological Association 3
  • Anticholinergic medications can help manage irritative bladder symptoms, according to the European Association of Urology 1
  • Non-steroidal anti-inflammatory drugs (NSAIDs) can be used for pain and inflammation, as recommended by the European Association of Urology 1
  • Fluoroquinolones may be considered as second-line agents for persistent symptoms, as suggested by the European Association of Urology 1
  • Inadequate follow-up can risk missed progression or recurrence, highlighting the importance of regular monitoring, as recommended by the National Comprehensive Cancer Network 2
  • Overuse of antibiotics when no bacterial infection is present should be avoided, as cautioned by the European Association of Urology 1