Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/3/2025

Respiratory and Infectious Disease Management

Upper Respiratory Tract Infections

  • The American College of Physicians recommends against prescribing antibiotics for upper respiratory tract infections, as they are typically viral in nature 1
  • Supportive care, including rest, hydration, and analgesics, is the primary treatment for upper respiratory tract infections 2

Lower Respiratory Tract Infections

  • The European Respiratory Society recommends amoxicillin as the first-line treatment for community-acquired pneumonia in adults, with a duration of 7-10 days 5
  • The Infectious Diseases Society of America recommends ceftriaxone plus a macrolide as the first-line treatment for hospitalized patients with community-acquired pneumonia 5

Skin and Soft Tissue Infections

  • The Infectious Diseases Society of America recommends cephalexin or dicloxacillin as the first-line treatment for uncomplicated cellulitis in adults 10
  • The American Academy of Pediatrics recommends cephalexin as the first-line treatment for uncomplicated cellulitis in pediatrics 10

Gastrointestinal Infections

  • The Infectious Diseases Society of America recommends nitrofurantoin or trimethoprim-sulfamethoxazole as the first-line treatment for uncomplicated urinary tract infections in adults 10
  • The American Academy of Pediatrics recommends amoxicillin-clavulanate as the first-line treatment for uncomplicated urinary tract infections in pediatrics 10

Allergic Reactions and Anaphylaxis

  • The American Academy of Allergy, Asthma, and Immunology recommends epinephrine as the first-line treatment for anaphylaxis in adults and pediatrics 10
  • The American Academy of Allergy, Asthma, and Immunology recommends diphenhydramine and corticosteroids as adjunctive treatments for anaphylaxis 10

Asthma Exacerbations

  • The National Asthma Education and Prevention Program recommends albuterol as the first-line treatment for asthma exacerbations in adults and pediatrics 10
  • The National Asthma Education and Prevention Program recommends ipratropium and corticosteroids as adjunctive treatments for asthma exacerbations 10

Migraine Headaches

  • The American Headache Society recommends sumatriptan as the first-line treatment for migraine headaches in adults 10
  • The American Headache Society recommends ibuprofen and metoclopramide as adjunctive treatments for migraine headaches in pediatrics 10