Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 12/16/2025

RAPID Trial Inclusion and Exclusion Criteria

Generalizability Limitations

  • The American Heart Association recommends that patients with atrioventricular-nodal-dependent PSVT be considered for treatment, but excludes other SVT mechanisms such as pre-excited atrial fibrillation where calcium channel blockers are contraindicated 1, 2
  • The American College of Cardiology guidelines suggest that hemodynamically unstable patients require immediate synchronized cardioversion rather than pharmacological therapy, and were therefore excluded from the trial 1, 3