Metoclopramide Use in Elderly Patients

Dosing and Alternative Approaches

• For adjunctive therapy in migraine treatment, the standard dose is 10 mg, but should be reduced in elderly patients, according to the American Academy of Family Physicians 1
• For nausea and vomiting in cancer patients, newer antiemetics such as 5-HT3 antagonists or NK1 receptor antagonists may be safer alternatives, as recommended by the National Comprehensive Cancer Network 2
• When using metoclopramide as an adjunctive therapy for migraine, consider other options like prochlorperazine if the patient is at high risk for extrapyramidal symptoms, as suggested by the American Academy of Family Physicians 1