Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/27/2025

Adenomyosis Diagnosis and Treatment

Symptoms and Diagnosis

  • Heavy or prolonged menstrual bleeding is a common symptom of adenomyosis, according to the American College of Radiology 1

Treatment Options

  • Hormonal treatments such as progestin IUDs have shown significant improvement in pain and bleeding in women with adenomyosis, as recommended by the American College of Radiology 2, 3
  • Combined oral contraceptives can help reduce painful and heavy menstrual bleeding in women with adenomyosis, as suggested by the American College of Radiology 2, 3
  • GnRH antagonists are effective for heavy menstrual bleeding even with concomitant adenomyosis, according to the American College of Radiology 2, 3
  • Uterine Artery Embolization (UAE) has shown promising results for women who desire to keep their uterus, with improvement in quality of life and symptom scores for up to 7 years, as reported by the American College of Radiology 2, 4
  • UAE results in short-term improvement in 94% and long-term improvement in 85% of patients, with about 7-18% of women eventually needing hysterectomy for persistent symptoms, according to the American College of Radiology 2, 4
  • Hysterectomy should be considered when other treatments fail and fertility preservation is not desired, as recommended by the American College of Radiology 2, 5

When to Seek Medical Attention

  • Menstrual bleeding that is heavy enough to disrupt daily activities is a reason to consult a healthcare provider, according to the American College of Radiology 1

REFERENCES