Normal Values for GFR and BUN:Creatinine Ratio

Normal GFR Values

The American College of Cardiology recommends that normal GFR in healthy young adults is approximately 100-130 mL/min/1.73 m² for men and 90-120 mL/min/1.73 m² for women, with values remaining stable until age 40 before physiologically declining 1
Young adults (under 40 years) with GFR values of approximately 100-130 mL/min/1.73 m² in men and 90-120 mL/min/1.73 m² in women represent normal kidney function 1
GFR ≥90 mL/min/1.73 m² is considered optimal kidney function and is the recommended threshold for living kidney donors 1
GFR 60-89 mL/min/1.73 m² represents mildly decreased kidney function but may be normal for older adults, particularly those over 70 years 1
GFR <60 mL/min/1.73 m² represents loss of half or more of normal adult kidney function and is the threshold for defining chronic kidney disease (CKD) 1, 2

The presence of other kidney damage markers, such as albuminuria or structural abnormalities on imaging, can make GFR values misleading, even if GFR >60 mL/min/1.73 m² 1
Body composition extremes, such as muscle mass or weight, can affect eGFR accuracy 1
Non-steady state conditions, such as acute illness or recent surgery, may produce inaccurate estimates 1
Hydration status significantly impacts measurements and should be considered when interpreting values 1
Serum creatinine should not be used to assess kidney function; always calculate GFR 1
CKD diagnosis requires persistent abnormalities for ≥3 months and should not be based solely on a single GFR measurement 1
Normal urinary albumin-to-creatinine ratio (UACR) is defined as <30 mg/g creatinine 2, 3
Both GFR and albuminuria should be assessed together, as an eGFR persistently <60 mL/min/1.73 m² in concert with urine albumin >30 mg/g creatinine is considered abnormal 3