Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 11/27/2025

Management of Panic Attacks with Lorazepam

Acute Panic Attack Management

  • The World Health Organization guidelines recommend psychological treatment based on Cognitive Behavioral Therapy (CBT) principles for individuals concerned about prior panic attacks, suggesting this should be the primary approach rather than medication alone 1
  • For immediate treatment of an active panic attack, lorazepam provides rapid relief of symptoms, according to the WHO guidelines 1

Critical Limitations and Warnings

Dependency and Withdrawal Risks

  • If discontinuation of lorazepam is needed, a gradual taper reducing by 10-25% of the current dose every 1-2 weeks is required, as recommended by medical guidelines 2

For Panic Disorder (Long-term Management)

  • Integrate CBT-based psychological treatment alongside medication, such as Selective Serotonin Reuptake Inhibitors (SSRIs), for long-term management of panic disorder 1