Trazodone Use During Pregnancy

Monitoring and Treatment Considerations

• For women requiring treatment for both depression and insomnia during pregnancy, careful monitoring of maternal and fetal health is recommended 1
• If alternative treatments are preferred, bupropion may be considered as it does not seem to be associated with major congenital malformations or other significant adverse obstetrical outcomes 1

Potential Risks to Consider

• While not specifically associated with trazodone, some antidepressants have been linked to poor neonatal adaptation syndrome, so monitoring of the newborn may be warranted 2