Corticosteroid Treatment for Acute Urticaria

Recommended Dosing and Efficacy

• Avoid courses shorter than the recommended 3-4 days, as inadequate duration can lead to rebound symptoms, according to Praxis Medical Insights 1

Concurrent Antihistamine Therapy

• The American Academy of Allergy, Asthma, and Immunology recommends combining corticosteroids with H1-antihistamines on a regular scheduled basis, with options including diphenhydramine 50 mg for rapid effect, and maintenance with hydroxyzine 25 mg every 4-8 hours or non-sedating antihistamines like cetirizine/loratadine 10 mg daily for daytime use, as supported by the Journal for ImmunoTherapy of Cancer 2