Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 9/2/2025

Diagnosis and Treatment of Sinusitis

Definition and Classification

  • The American Academy of Allergy, Asthma, and Immunology defines sinusitis as the inflammation of one or more paranasal sinuses, with infection being the most common cause 2
  • Sinusitis is classified based on duration into: acute sinusitis (symptoms for less than 4 weeks) 3, subacute sinusitis (symptoms for 4 to 8 weeks) 4, chronic sinusitis (symptoms for 8 weeks or more) 4, and recurrent sinusitis (3 or more episodes of acute sinusitis per year) 4

Diagnosis

  • The diagnosis of acute sinusitis is primarily clinical, based on persistent symptoms of upper respiratory infection beyond 10-14 days 8, 7
  • The American Academy of Allergy, Asthma, and Immunology recommends that computed tomography (CT) scans without contrast are the imaging technique of choice when symptoms are vague 7 or when the disease persists despite optimal medical treatment 10
  • Nasal endoscopy can be useful for directly visualizing anomalies of the septum, turbinates, mucosa, and nasopharynx 8

Treatment

  • The American Academy of Allergy, Asthma, and Immunology recommends amoxicillin as the first-line antibiotic for children and adults 1, 5
  • The use of intranasal corticosteroids can be useful in patients with acute and chronic sinusitis 3, 9
  • Short-term use of oral corticosteroids may be considered when the patient does not respond to initial treatment 5, has nasal polyps 5, or shows marked mucosal edema 3

Special Considerations

  • For patients with chronic sinusitis, consideration should be given to a non-infectious form of sinusitis (chronic hyperplastic eosinophilic rhinosinusitis) 4
  • A course of systemic corticosteroids may be necessary 6
  • Evaluation should include coronal sinus CT scans 6
  • In cases of chronic sinusitis resistant to medical treatment, consideration should be given to consultation with an otolaryngologist for possible surgical intervention 6

Complications and Warning Signs

  • Warning signs of complications include facial swelling or erythema over an affected sinus 3, changes in vision 3, abnormal extraocular movements 3, proptosis 3, periorbital inflammation/edema/erythema 3, or any suggestion of intracranial or central nervous system involvement 1, 9