Praxis Medical Insights

Est. 2024 • Clinical Guidelines Distilled

Made possible by volunteer editors from the University of Calgary & University of Alberta

Last Updated: 8/29/2025

Microneedling for Surgical Scar Improvement

Mechanism of Action

  • Microneedling works through "minimally invasive percutaneous collagen induction," creating controlled micro-injuries that stimulate neovascularization, neocollagenesis, and tissue repair 1
  • Histological studies show improvements in skin thickness, hydration, and normalization of collagen/elastin matrix in the reticular dermis 2, 3
  • The collagen produced after microneedling treatment appears in a normal lattice pattern rather than parallel bundles typically seen in scars 3

Enhanced Results with Combination Therapy

  • Microneedling combined with autologous platelet concentrates (APCs) such as PRP (platelet-rich plasma) or PRF (platelet-rich fibrin) is more effective than microneedling alone 4, 5
  • Studies indicate that PRF may be more effective than PRP when combined with microneedling for scar improvement 5
  • The application timing of APCs is important - applying PRP or PRF prior to microneedling shows better results than application after the procedure 4
  • Patient satisfaction is typically higher with combined microneedling and PRP/PRF treatments compared to microneedling alone 6

Optimal Treatment Protocol

  • For optimal results, patients should undergo 3-4 monthly microneedling treatment sessions 1
  • Treatments should be spaced at least one month apart to allow for proper healing between sessions 1
  • Maintenance treatments may be recommended every 6 months for continued improvement 5
  • Needle depth should be adjusted based on the treatment area, typically between 0.25-2.5 mm 2

Safety Profile and Considerations

  • Microneedling is considered a safe therapy with minimal damage to the skin and shorter downtime (24-48 hours) compared to ablative techniques 2
  • Ensure proper skin preparation and sterilization to minimize infection risk 2
  • Patients should avoid sun exposure and heavily scented facial products for 24 hours post-treatment 2